Abstract
Transarterial radioembolization (TARE) using yttrium-90 (90Y)-labeled microspheres has become increasingly adopted as an important treatment
option for primary and metastatic hepatic malignancies. Rigorous patient evaluation
and selection prior to TARE is critical to optimize the benefits of this therapy and
minimize adverse events. Equally important for ensuring a successful 90Y program is a broad knowledge of the fundamental physical characteristics, manufacturing
processes, and supply and delivery parameters of the different commercially available
microspheres and those currently under investigation for use in the United States.
Keywords
transarterial radioembolization - patient selection - radioembolization-induced liver
disease